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Mesothelioma

Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma

 

Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma

Background:
Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill cancer cells. Combining photodynamic therapy with surgery may be an effective treatment for malignant mesothelioma. This a Phase II trial to study the effectiveness of combining photodynamic therapy with surgery in treating patients who have malignant mesothelioma.

Inclusion Criteria:
Histologically or cytologically confirmed malignant mesothelioma, including the following cell types:

Mixed mesothelial
Sarcomatous
Stage I or II disease using the Buchart system as determined by CT scan or MRI
Disease confined to 1 hemithorax
No tumor involvement of esophagus or heart as evidenced by CT scan
Pericardial or diaphragmatic involvement allowed if disease is limited to the ipsilateral chest
N2 disease allowed if no contralateral pleural involvement
No adenocarcinoma or nonmesotheliomasarcoma of the chest wall

Location/Contact Information:
New York
Roswell Park Cancer Institute,
Buffalo, New York, 14263-0001, United States;
Recruiting
Timothy M. Anderson, MD 716-845-5873
timothy.anderson@roswellpark.org

Study chairs or principal investigators
Timothy M. Anderson, MD, Study Chair
Roswell Park Cancer Institute